Anti-Human VISTA/B7-H5/PD-1H Reference Antibody (Onvatilimab, RUO) (HP543016)

Name: Anti-Human VISTA/B7-H5/PD-1H Reference Antibody (Onvatilimab, RUO)
Brand: abinScience
SKU: HP543016
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
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25mg
50mg
100mg

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Vista general

Número de catálogo	HP543016
Descripción	Onvatilimab (HP543016) is a research-grade recombinant antibody targeting V-set domain-containing immunoregulatory receptor. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1-kappa
Sistema de expresión	Mammalian cells
Objetivo	V-set domain-containing immunoregulatory receptor, C10orf54, VSIR, VISTA, SISP1, Stress-induced secreted protein-1, Platelet receptor Gi24, V-set immunoregulatory receptor, Sisp-1, V-type immunoglobulin domain-containing suppressor of T-cell activation
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q9H7M9
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	JNJ-61610588, 1969313-51-6
Fondo	V-type immunoglobulin domain-containing suppressor of T-cell activation (VSIR/VISTA) is a ~33 kDa protein. Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14-mediated MMP2 activation. 1. Lines, JL. et al. (2014) Cancer research 74, 1924-32. PMID: 24691993 2. Sakr, MA. et al. (2010) Cancer science 101, 2368-74. PMID: 20666777
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Imágenes

Bioactivity

Detects Human VSIR/VISTA in indirect ELISAs.
Bioactivity

SEC-HPLC detection for Research Grade Onvatilimab.
SDS-PAGE

SDS-PAGE for Anti-Human VISTA/B7-H5/PD-1H Reference Antibody (Onvatilimab, RUO)