Anti-Human CTGF/CCN2 Reference Antibody (Pamrevlumab, RUO) (HB719016)

Name: Anti-Human CTGF/CCN2 Reference Antibody (Pamrevlumab, RUO)
Brand: abinScience
SKU: HB719016
Price: 176 USD
Availability: InStock

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Numéro de catalogue	HB719016
Description	Research Grade Pamrevlumab (HB719016) is a human monoclonal antibody detecting IGFBP8 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-kappa
Système d'expression	Mammalian cells
Espèces	Human
Cible	IGFBP8, IGF-binding protein 8, IBP-8, CTGF, HCS24, CCN family member 2, CCN2, Cellular communication network factor 2, Hypertrophic chondrocyte-specific protein 24, Connective tissue growth factor, Insulin-like growth factor-binding protein 8, IGFBP-8
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P29279
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	FG-3019, 946415-13-0
Contexte	CCN family member 2 (IGFBP8,IGF-binding protein 8,IBP-8,CTGF,HCS24,CCN family member 2,CCN2,Cellular communication network factor 2,Hypertrophic chondrocyte-specific protein 24,Connective tissue growth factor,Insulin-like growth factor-binding protein 8,IGFBP-8) is a ~38 kDa protein. Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. 1. Li, S. et al. (2024) Bone research 12, 60. PMID: 39414788
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)