Anti-Human CTGF/CCN2 Recombinant Antibody (SAA0452) (HB719107)

Name: Anti-Human CTGF/CCN2 Recombinant Antibody (SAA0452)
Brand: abinScience
SKU: HB719107
Price: 196 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.	HB719107
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	SAA0452
Clonality	Monoclonal
Target	IGFBP8, IGF-binding protein 8, IBP-8, CTGF, HCS24, CCN family member 2, CCN2, Cellular communication network factor 2, Hypertrophic chondrocyte-specific protein 24, Connective tissue growth factor, Insulin-like growth factor-binding protein 8, IGFBP-8
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P29279
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	CCN family member 2 (CTGF/CCN2) is a ~38 kDa protein. Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. 1. Li, S. et al. (2024) Bone research 12, 60. PMID: 39414788
Note	For research use only.

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Bioactivity

SEC-HPLC detection for Anti-Human CTGF/CCN2 Antibody (ABS2063).
Flow Cytometry

Flow-cytometry using anti-human CTGF antibody.CTGF Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CTGF antibody monoclonal antibody (Catalog # HB719107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow Cytometry

Flow-cytometry using anti-human CTGF antibody.HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CTGF antibody monoclonal antibody (Catalog # HB719107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.