

| Catalog No. | HB719137 |
|---|---|
| Species reactivity | Human |
| Applications | ELISA, FCM |
| Host species | Mouse |
| Isotype | IgG1, kappa |
| Clone ID | SAA0452 |
| Conjugation | APC |
| Clonality | Monoclonal |
| Target | IGFBP8, IGF-binding protein 8, IBP-8, CTGF, HCS24, CCN family member 2, CCN2, Cellular communication network factor 2, Hypertrophic chondrocyte-specific protein 24, Connective tissue growth factor, Insulin-like growth factor-binding protein 8, IGFBP-8 |
| Endotoxin level | Please contact with the lab for this information. |
| Associated products | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC |
| Accession | P29279 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | CCN family member 2 (CTGF/CCN2) is a ~38 kDa protein. Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. 1. Li, S. et al. (2024) Bone research 12, 60. PMID: 39414788 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |

Flow-cytometry using APC anti-human CTGF antibody. MG-63 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CTGF monoclonal antibody (Catalog: HB719137, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.




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