Anti-Human CTGF/CCN2 Reference Antibody (Pamrevlumab, RUO) (HB719016)

Name: Anti-Human CTGF/CCN2 Reference Antibody (Pamrevlumab, RUO)
Brand: abinScience
SKU: HB719016
Price: 176 USD
Availability: InStock

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概要
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データシート
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概要

カタログ番号	HB719016
説明	Research Grade Pamrevlumab (HB719016) is a human monoclonal antibody detecting IGFBP8 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1-kappa
発現システム	Mammalian cells
種	Human
ターゲット	IGFBP8, IGF-binding protein 8, IBP-8, CTGF, HCS24, CCN family member 2, CCN2, Cellular communication network factor 2, Hypertrophic chondrocyte-specific protein 24, Connective tissue growth factor, Insulin-like growth factor-binding protein 8, IGFBP-8
エンドトキシンレベル	< 10 EU/mg
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P29279
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	FG-3019, 946415-13-0
背景	CCN family member 2 (IGFBP8,IGF-binding protein 8,IBP-8,CTGF,HCS24,CCN family member 2,CCN2,Cellular communication network factor 2,Hypertrophic chondrocyte-specific protein 24,Connective tissue growth factor,Insulin-like growth factor-binding protein 8,IGFBP-8) is a ~38 kDa protein. Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. 1. Li, S. et al. (2024) Bone research 12, 60. PMID: 39414788
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)