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Anti-Human Nectin-2/CD112 Reference Antibody (Remzistotug, RUO) (HV456016)

Anti-Human Nectin-2/CD112 Reference Antibody (Remzistotug, RUO)
Anti-Human Nectin-2/CD112 Reference Antibody (Remzistotug, RUO)
Precio(USD):
Especificación:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Número:
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  • Vista general

  • Imágenes

  • Referencias

  • Datasheet

  • SDS

Vista general
Número de catálogoHV456016
Descripción
remzistotug (HV456016) is a research-grade recombinant antibody targeting CD112.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
Reactividad de especiesHuman
AplicacionesELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG1, Kappa
Especies Human
Objetivo CD112/Nectin-2/PVRL2
Nivel de endotoxinas < 10 EU/mg
Pureza >95% as determined by SDS-PAGE.
Número de acceso Q92692
Forma Liquid
Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos2920425-39-2
Fondo

Nectin-2 (CD112/PVRL2) is a ~57 kDa protein. Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive.

1. Zhu, Y. et al. (2016) The Journal of experimental medicine 213, 167-76. PMID: 26755705
2. Warner, MS. et al. (1998) Virology 246, 179-89. PMID: 9657005
Nota For research use only. Not suitable for clinical or therapeutic use.
Imágenes
  • Anti-Human Nectin-2/CD112 Reference Antibody (Remzistotug, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade remzistotug

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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