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Anti-Human SOST/Sclerostin Reference Antibody (Setrusumab, RUO) (HV185036)

Anti-Human SOST/Sclerostin Reference Antibody (Setrusumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Setrusumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Setrusumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Setrusumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Setrusumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Setrusumab, RUO)
Precio(USD):
Especificación:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Número:
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  • Imágenes

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Vista general
Número de catálogoHV185036
Descripción
Setrusumab (HV185036) is a research-grade recombinant antibody targeting SOST. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especiesHuman
AplicacionesELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG2-lambda
Sistema de expresión Mammalian cells
Objetivo SOST, Sclerostin
Nivel de endotoxinas < 10 EU/mg
Pureza >95% purity as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q9BQB4
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosBPS-804, MOR-05813, 1847394-95-9
Fondo

Sclerostin (SOST) is a ~24 kDa protein. Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

Nota For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)
Imágenes
  • Anti-Human SOST/Sclerostin Reference Antibody (Setrusumab, RUO)

    SEC-HPLC

    SEC-HPLC detection for Research Grade Setrusumab.

  • Anti-Human SOST/Sclerostin Reference Antibody (Setrusumab, RUO)

    Bioactivity

    Detects SOST in indirect ELISAs.

  • Anti-Human SOST/Sclerostin Reference Antibody (Setrusumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Setrusumab.

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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