Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO) (HV185016)

Name: Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)
Brand: abinScience
SKU: HV185016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HV185016
Description	Romosozumab (HV185016) is a research-grade recombinant antibody targeting SOST. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG2-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	SOST, Sclerostin
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9BQB4
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	785A070802, AMG785, CDP-7851, romosozumab-aqqg, sclerostinAb, CAS: 909395-70-6
Background	Sclerostin (SOST) is a ~24 kDa protein. Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Note	For research use only. Not suitable for clinical or therapeutic use.