Anti-Human APOC3 Reference Antibody (Stt-5058, RUO) (HF594016)

Name: Anti-Human APOC3 Reference Antibody (Stt-5058, RUO)
Brand: abinScience
SKU: HF594016
Price: 176 USD
Availability: InStock

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Numéro de catalogue	HF594016
Description	STT-5058 (HF594016) is a research-grade recombinant antibody targeting APOC3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-Kappa
Système d'expression	Mammalian cells
Cible	APOC3, Apolipoprotein C3, Apo-CIII, Apolipoprotein C-III, ApoC-III
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P02656
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	ARGX-116
Contexte	Apolipoprotein C-III (ApoC3) is a ~10 kDa protein. Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners. 1. Chan, DC. et al. (2008) International journal of clinical practice 62, 799-809. PMID: 18201179 2. Yao, Z. et al. (2012) Current opinion in lipidology 23, 206-212. PMID: 22510806 3. Gangabadage, CS. et al. (2008) The Journal of biological chemistry 283, 17416-27. PMID: 18408013
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

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SDS-PAGE for Research Grade STT-5058

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Anti-Human APOC3 Reference Antibody (Stt-5058, RUO).pdf

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