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Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Urelumab, RUO) (HC336026)

Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Urelumab, RUO)
Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Urelumab, RUO)
Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Urelumab, RUO)
Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Urelumab, RUO)
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Spécification :
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
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Aperçu
Numéro de catalogueHC336026
Description
Urelumab (HC336026) is a research-grade recombinant antibody targeting CD137. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG4-kappa
Cible 4-1BB ligand receptor, CD137, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, Tumor necrosis factor receptor superfamily member 9
Niveau d'endotoxines < 10 EU/mg
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q07011
Forme Liquid
Tampon de stockage 0.94 mM Citricacid, 16.7mM Trisodiumcitratedihydrate, 6.2% sucrose, pH 6.5, 0.01% Tween80

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsBMS-663513, 934823-49-1
Contexte

Tumor necrosis factor receptor superfamily member 9 (CD137/4-1BB) is a ~27 kDa protein. Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).

Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Human IgG4 (S228P & L235E) Recombinant Isotype Control Antibody (HyHEL-10) (HP614107)
Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)
Images
  • Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Urelumab, RUO)

    Bioactivity

    Detects Human CD137/TNFRSF9 in indirect ELISAs.

  • Anti-Human 4-1BB/TNFRSF9/CD137 Reference Antibody (Urelumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Urelumab.

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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