Anti-Human Integrin alpha 2/CD49b Reference Antibody (Vatelizumab, RUO) (HB772016)

Name: Anti-Human Integrin alpha 2/CD49b Reference Antibody (Vatelizumab, RUO)
Brand: abinScience
SKU: HB772016
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
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Referencias
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SDS

Vista general

Número de catálogo	HB772016
Descripción	Vatelizumab (HB772016) is a research-grade recombinant antibody targeting CD49B. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG4-kappa
Sistema de expresión	Mammalian cells
Objetivo	Collagen receptor, ITGA2, VLA-2 subunit alpha, CD49B, CD49 antigen-like family member B, Platelet membrane glycoprotein Ia, GPIa, Integrin alpha-2, CD49b
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P17301
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	GBR500, 1238217-55-4
Fondo	Integrin alpha-2 (CD49b/ITGA2) is a ~129 kDa protein. Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)

Imágenes

SDS-PAGE

SDS-PAGE for Research Grade Vatelizumab.
Flow CytoMetry

Flow-cytometry using APC anti-human CD49b antibody. HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD49b monoclonal antibody (Catalog: HB772016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using FITC anti-human CD49b antibody. HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD49b monoclonal antibody (Catalog: HB772016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using PE anti-human CD49b antibody. HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD49b monoclonal antibody (Catalog: HB772016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.