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Anti-Human CD49b/ITGA2 Recombinant Antibody (SAA0018), APC (HB772137)

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Anti-Human CD49b/ITGA2 Recombinant Antibody (SAA0018), APC

Anti-Human CD49b/ITGA2 Recombinant Antibody (SAA0018), APC

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Overview

Catalog No.	HB772137
Description	Anti-Human CD49b/ITGA2 Antibody (SAA0018), APC [SAA0018] (HB772137) is a mouse monoclonal antibody detecting ITGA2 in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0018
Conjugation	APC
Clonality	Monoclonal
Target	Collagen receptor, ITGA2, VLA-2 subunit alpha, CD49B, CD49 antigen-like family member B, Platelet membrane glycoprotein Ia, GPIa, Integrin alpha-2, CD49b
Endotoxin level	Please contact with the lab for this information.
Accession	P17301
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Integrin alpha-2 (CD49b/ITGA2) is a ~129 kDa protein. Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Images

Flow CytoMetry

Flow-cytometry using APC anti-human CD49b antibody. HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD49b monoclonal antibody (Catalog: HB772137, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet

Anti-Human CD49b/ITGA2 Recombinant Antibody (SAA0018), APC.pdf

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Anti-Human CD49b/ITGA2 Recombinant Antibody (SAA0018), APC