Anti-AAV2 Capsids (intact particle) Recombinant Antibody (A20) (VK683043)

Name: Anti-AAV2 Capsids (intact particle) Recombinant Antibody (A20)
Brand: abinScience
SKU: VK683043
Price: 191 USD
Availability: InStock

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Spécification :

50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

VK683043

Reactivité des espèces

Adeno-associated virus 2 (AAV2)

Applications

Dot blot, ELISA, ICC/IF, IP, Neutralization

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG3

ID de clone

A20

Cible

Capsid protein VP1, VP1

Niveau d'endotoxines

<10 EU/mg

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P03135

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Contexte

Capsid protein VP1 is a ~81 kDa protein. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of three size variants of the capsid protein VP1, VP2 and VP3 which differ in their N-terminus. The capsid encapsulates the genomic ssDNA. Binds to host cell heparan sulfate and uses host ITGA5-ITGB1 as coreceptor on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptor also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and putative nuclear localization signal(s).

Note

For research use only

Images