Anti-AAV2 Capsids (intact particle) Recombinant Antibody (A20R) (VK683033)

Name: Anti-AAV2 Capsids (intact particle) Recombinant Antibody (A20R)
Brand: abinScience
SKU: VK683033
Price: 191 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

VK683033

Reactividad de especies

Adeno-associated virus 2 (AAV2)

Aplicaciones

Dot blot, ELISA, ICC/IF, IP, Neutralization

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG1

ID de clon

A20R

Objetivo

Capsid protein VP1, VP1

Nivel de endotoxinas

<10 EU/mg

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P03135

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Fondo

Capsid protein VP1 is a ~81 kDa protein. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of three size variants of the capsid protein VP1, VP2 and VP3 which differ in their N-terminus. The capsid encapsulates the genomic ssDNA. Binds to host cell heparan sulfate and uses host ITGA5-ITGB1 as coreceptor on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptor also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and putative nuclear localization signal(s).

Nota

For research use only

Imágenes