

| Каталожный номер | HX089015 |
|---|---|
| Описание |
Anti-Human CAV1 Monoclonal Antibody (1A514) [1A514] (HX089015) is a mouse monoclonal antibody detecting CAV1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| Реактивность видов | Human |
| Применения | ELISA, IHC, WB |
| Хозяинский вид | Mouse |
| Клоональность | Monoclonal |
| Изотип | IgG |
| ID клона | 1A514 |
| Иммуноген | E. coli - derived recombinant human CAV1 (Met1-Ser104). |
| Цель | Caveolin-1, CAV1 |
| Уровень эндотоксинов | < 10 EU/mg |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q03135 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Фон | Caveolin-1 (CAV1) is a ~20 kDa protein. May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. 1. Vargas, L. et al. (2002) The Journal of biological chemistry 277, 9351-7. PMID: 11751885 2. McMahon, KA. et al. (2009) The EMBO journal 28, 1001-15. PMID: 19262564 3. Ohnuma, K. et al. (2007) The Journal of biological chemistry 282, 10117-10131. PMID: 17287217 4. Hwangbo, C. et al. (2016) Oncogene 35, 389-401. PMID: 25893292 |
| Примечание | For research use only. |

SDS-PAGE for Anti-Human CAV1 Monoclonal Antibody (1A514)




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