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Anti-Human CAV1/Caveolin-1 Monoclonal Antibody (1A514) (HX089015)

Anti-Human CAV1/Caveolin-1 Monoclonal Antibody (1A514)
Anti-Human CAV1/Caveolin-1 Monoclonal Antibody (1A514)
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Обзор
Каталожный номерHX089015
Описание
Anti-Human CAV1 Monoclonal Antibody (1A514) [1A514] (HX089015) is a mouse monoclonal antibody detecting CAV1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
Реактивность видовHuman
ПримененияELISA, IHC, WB
Хозяинский видMouse
КлоональностьMonoclonal
ИзотипIgG
ID клона1A514
Иммуноген E. coli - derived recombinant human CAV1 (Met1-Ser104).
Цель Caveolin-1, CAV1
Уровень эндотоксинов < 10 EU/mg
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q03135
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Caveolin-1 (CAV1) is a ~20 kDa protein. May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.

1. Vargas, L. et al. (2002) The Journal of biological chemistry 277, 9351-7. PMID: 11751885
2. McMahon, KA. et al. (2009) The EMBO journal 28, 1001-15. PMID: 19262564
3. Ohnuma, K. et al. (2007) The Journal of biological chemistry 282, 10117-10131. PMID: 17287217
4. Hwangbo, C. et al. (2016) Oncogene 35, 389-401. PMID: 25893292
Примечание For research use only.
Изображения
  • Anti-Human CAV1/Caveolin-1 Monoclonal Antibody (1A514)

    SDS-PAGE

    SDS-PAGE for Anti-Human CAV1 Monoclonal Antibody (1A514)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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