Anti-Human CD261/TNFRSF10A/DR4 Recombinant Antibody (SAA2670), PE (HT017227)

Name: Anti-Human CD261/TNFRSF10A/DR4 Recombinant Antibody (SAA2670), PE
Brand: abinScience
SKU: HT017227
Price: 290 USD
Availability: InStock

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Numéro de catalogue	HT017227
Reactivité des espèces	Human
Applications	FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
ID de clone	SAA2670
Conjugaison	PE
Cible	APO2, CD261, DR4, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, TRAILR1, Tumor necrosis factor receptor superfamily member 10A
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	O00220
Forme	Liquid
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Tumor necrosis factor receptor superfamily member 10A (CD261/TNFRSF10A) is a ~50 kDa protein. Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. 1. Ramamurthy, V. et al. (2015) Acta crystallographica. Section F, Structural biology communications 71, 1273-81. PMID: 26457518 2. Chyuan, IT. et al. (2024) Journal of biomedical science 31, 33. PMID: 38532423 3. Rossin, A. et al. (2009) The Biochemical journal 419, 185-92, 2 p following 192. PMID: 19090789 4. Chaudhary, PM. et al. (1997) Immunity 7, 821-30. PMID: 9430227
Note	For research use only

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Anti-Human CD261/TNFRSF10A/DR4 Recombinant Antibody (SAA2670), PE.pdf

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