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Anti-Human CD339/JAG1 Recombinant Antibody (B70), FITC (HX118117)

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Aperçu
Numéro de catalogueHX118117
Reactivité des espècesHuman, Mouse
ApplicationsFCM
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneB70
ConjugaisonFITC
Cible JAG1, Jagged1, CD339, JAGL1, Protein jagged-1, hJ1
Niveau d'endotoxines Please contact with the lab for this information.
Produits associés Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), FITC
Numéro d'accès P78504
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

Protein jagged-1 (CD339/JAG1) is a ~133 kDa protein. Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro).

1. Cordle, J. et al. (2008) Nature structural & molecular biology 15, 849-57. PMID: 18660822
2. Bauer, RC. et al. (2010) Human mutation 31, 594-601. PMID: 20437614
3. Li, L. et al. (1998) Immunity 8, 43-55. PMID: 9462510
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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