Anti-Human CD82 Recombinant Antibody (SAA1615) (HB018013)

Name: Anti-Human CD82 Recombinant Antibody (SAA1615)
Brand: abinScience
SKU: HB018013
Price: 196 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HB018013

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA1615

Objetivo

IA4, Tspan-27, Metastasis suppressor Kangai-1, Inducible membrane protein R2, Suppressor of tumorigenicity 6 protein, KAI1, TSPAN27, CD82, SAR2, C33 antigen, ST6, Tetraspanin-27, CD82 antigen

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P27701

RRID

Anti-Human CD82 Antibody (SAA1615) (abinScience Cat# HB018013, RRID:AB_3727376)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

CD82 antigen is a ~29 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Acts as a attenuator of EGF signaling, facilitating ligand-induced endocytosis of the receptor and its subsequent desensitization. Mechanistically, modulates ligand-induced ubiquitination and trafficking of EGFR via E3 ligase CBL phosphorylation by PKC. Increases cell-matrix adhesion by regulating the membrane organization of integrin alpha4/ITA4.

1. Xu, C. et al. (2009) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23, 3273-88. PMID: 19497983

2. Odintsova, E. et al. (2000) Current biology : CB 10, 1009-12. PMID: 10985391

3. Bu, J. et al. (2022) Acta biochimica et biophysica Sinica 54, 400-408. PMID: 35538033

4. Odintsova, E. et al. (2013) The Journal of biological chemistry 288, 26323-26334. PMID: 23897813

5. Termini, CM. et al. (2014) Molecular biology of the cell 25, 1560-73. PMID: 24623721

6. Mannion, BA. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 2039-47. PMID: 8757325

7. He, B. et al. (2005) The Journal of biological chemistry 280, 3346-54. PMID: 15557282

8. Jee, BK. et al. (2007) Biochemical and biophysical research communications 359, 703-8. PMID: 17560548

9. Bass, R. et al. (2005) The Journal of biological chemistry 280, 14811-8. PMID: 15677461

10. Lee, H. et al. (2023) BMB reports 56, 359-364. PMID: 36945827

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human CD82 Antibody (SAA1615)

Referencias

Datasheet

Anti-Human CD82 Recombinant Antibody (SAA1615).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo