Anti-Human CD82 Recombinant Antibody (SAA1615) (HB018013)

Name: Anti-Human CD82 Recombinant Antibody (SAA1615)
Brand: abinScience
SKU: HB018013
Price: 196 USD
Availability: InStock

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Prix(USD) :

Spécification :

50ug
100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HB018013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1615

Cible

IA4, Tspan-27, Metastasis suppressor Kangai-1, Inducible membrane protein R2, Suppressor of tumorigenicity 6 protein, KAI1, TSPAN27, CD82, SAR2, C33 antigen, ST6, Tetraspanin-27, CD82 antigen

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P27701

RRID

Anti-Human CD82 Antibody (SAA1615) (abinScience Cat# HB018013, RRID:AB_3727376)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

CD82 antigen is a ~29 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Acts as a attenuator of EGF signaling, facilitating ligand-induced endocytosis of the receptor and its subsequent desensitization. Mechanistically, modulates ligand-induced ubiquitination and trafficking of EGFR via E3 ligase CBL phosphorylation by PKC. Increases cell-matrix adhesion by regulating the membrane organization of integrin alpha4/ITA4.

1. Xu, C. et al. (2009) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23, 3273-88. PMID: 19497983

2. Odintsova, E. et al. (2000) Current biology : CB 10, 1009-12. PMID: 10985391

3. Bu, J. et al. (2022) Acta biochimica et biophysica Sinica 54, 400-408. PMID: 35538033

4. Odintsova, E. et al. (2013) The Journal of biological chemistry 288, 26323-26334. PMID: 23897813

5. Termini, CM. et al. (2014) Molecular biology of the cell 25, 1560-73. PMID: 24623721

6. Mannion, BA. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 2039-47. PMID: 8757325

7. He, B. et al. (2005) The Journal of biological chemistry 280, 3346-54. PMID: 15557282

8. Jee, BK. et al. (2007) Biochemical and biophysical research communications 359, 703-8. PMID: 17560548

9. Bass, R. et al. (2005) The Journal of biological chemistry 280, 14811-8. PMID: 15677461

10. Lee, H. et al. (2023) BMB reports 56, 359-364. PMID: 36945827

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CD82 Antibody (SAA1615)

Reférences

Fiche technique

Anti-Human CD82 Recombinant Antibody (SAA1615).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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