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| カタログ番号 | HT495023 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | FCM, ICC, IF, IHC, WB | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | scFv-His | ||||
| クローンID | AC133/1 | ||||
| ターゲット | Prominin-1, Antigen AC133, Prominin-like protein 1, CD133, PROM1, PROML1, MSTP061 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | O43490 | ||||
| RRID | Anti-Human Glycosylated CD133/PROM1 Antibody (AC133/1) (abinScience Cat# HT495023, RRID:AB_3729293) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Prominin-1 (Glycosylated CD133) is a ~97 kDa protein. May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner. 1. Mak, AB. et al. (2014) Journal of molecular biology 426, 2175-82. PMID: 24556617 2. Takenobu, H. et al. (2011) Oncogene 30, 97-105. PMID: 20818439 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human Glycosylated CD133/PROM1 Antibody (AC133/1)
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