Human CD300LF Recombinant Protein (C-Fc) (HV211021)

Name: Human CD300LF Recombinant Protein (C-Fc)
Brand: abinScience
SKU: HV211021
Price: 298 USD
Availability: InStock

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50ug
100ug
1mg

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HV211021
説明	Recombinant Human CD300LF Protein, C-Fc (HV211021) expressed in Mammalian Cells, spanning Thr20-Leu155. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
発現システム	Mammalian cells
アクセッション番号	Q8TDQ1
タンパク質長	Thr20-Leu155
アプリケーション	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種	Homo sapiens (Human)
性質	Recombinant
エンドトキシンレベル	Please contact with the lab for this information.
純度	>90% as determined by SDS-PAGE.
予測分子量	43.74 kDa
形態	Lyophilized
保存バッファー	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
再構成	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	CD300 antigen-like family member F, CD300F, CD300LF, CD300f, CLM-1, CLM1, CMRF35-like molecule 1, IGSF13, IREM-1, IREM1, IgSF13, Immune receptor expressed on myeloid cells 1, Immunoglobulin superfamily member 13, NK inhibitory receptor, NKIR
背景	CMRF35-like molecule 1 is a ~32 kDa protein. Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands. May act as a coreceptor for interleukin 4 (IL-4). 1. Alvarez-Errico, D. et al. (2004) European journal of immunology 34, 3690-701. PMID: 15549731 2. Izawa, K. et al. (2014) The Journal of allergy and clinical immunology 133, 270-3.e1-7. PMID: 24035150 3. Kim, EJ. et al. (2012) Immunology 135, 226-35. PMID: 22043923
注意事項	For research use only