Anti-Human CD300LF Polyclonal Antibody (HV211014)

Name: Anti-Human CD300LF Polyclonal Antibody
Brand: abinScience
SKU: HV211014
Price: 168 USD
Availability: InStock

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Overview

Catalog No.

HV211014

Description

Anti-Human CD300LF Polyclonal Antibody (HV211014) is a rabbit polyclonal antibody detecting CMRF35-like molecule 1; CLM-1; CD300 antigen-like family member F; Immune receptor expressed on myeloid cells 1; IREM-1; Immunoglobulin superfamily member 13; IgSF13; NK inhibitory receptor; CD300f; CD300LF; CD300F; CLM1; IGSF13; IREM1; NKIR; UNQ3105/PRO10111 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant human CD300LF (Thr20-Leu155).

Target

CMRF35-like molecule 1; CLM-1; CD300 antigen-like family member F; Immune receptor expressed on myeloid cells 1; IREM-1; Immunoglobulin superfamily member 13; IgSF13; NK inhibitory receptor; CD300f; CD300LF; CD300F; CLM1; IGSF13; IREM1; NKIR; UNQ3105/PRO10111

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q8TDQ1

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

CMRF35-like molecule 1 (CD300LF) is a ~32 kDa protein. Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands. May act as a coreceptor for interleukin 4 (IL-4).

1. Alvarez-Errico, D. et al. (2004) European journal of immunology 34, 3690-701. PMID: 15549731

2. Izawa, K. et al. (2014) The Journal of allergy and clinical immunology 133, 270-3.e1-7. PMID: 24035150

3. Kim, EJ. et al. (2012) Immunology 135, 226-35. PMID: 22043923

Note

For research use only

Images

References

Datasheet

Anti-Human CD300LF Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-Human CD300LF Polyclonal Antibody (HV211014)

Overview

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References

Datasheet

SDS

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