Anti-Human CD300f/CD300LF Recombinant Antibody (SAA1608) (HV211013)

Name: Anti-Human CD300f/CD300LF Recombinant Antibody (SAA1608)
Brand: abinScience
SKU: HV211013
Price: 196 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV211013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1608

Clonality

Monoclonal

Target

IREM1, Immunoglobulin superfamily member 13, NK inhibitory receptor, CD300 antigen-like family member F, CD300F, CD300LF, CLM-1, IGSF13, NKIR, IREM-1, Immune receptor expressed on myeloid cells 1, CMRF35-like molecule 1, CD300f, IgSF13, CLM1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8TDQ1

RRID

Anti-Human CD300f/CD300LF Antibody (SAA1608) (abinScience Cat# HV211013, RRID:AB_3727369)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

CMRF35-like molecule 1 (CD300f/CD300LF) is a ~32 kDa protein. Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands. May act as a coreceptor for interleukin 4 (IL-4).

1. Alvarez-Errico, D. et al. (2004) European journal of immunology 34, 3690-701. PMID: 15549731

2. Izawa, K. et al. (2014) The Journal of allergy and clinical immunology 133, 270-3.e1-7. PMID: 24035150

3. Kim, EJ. et al. (2012) Immunology 135, 226-35. PMID: 22043923

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CD300f/CD300LF Antibody (SAA1608)

References

Datasheet

Anti-Human CD300f/CD300LF Recombinant Antibody (SAA1608).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CD300f/CD300LF Recombinant Antibody (SAA1608) (HV211013)

Overview

Images

References

Datasheet

SDS

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