Human CD82 Recombinant Protein (C-Fc) (HB018021)

Name: Human CD82 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: HB018021
Price: 298 USD
Availability: InStock

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50ug
100ug
1mg

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HB018021
説明	Recombinant Human CD82 Protein, C-Fc (HB018021) expressed in Mammalian Cells, spanning Gly111-Leu228. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
発現システム	Mammalian cells
アクセッション番号	P27701
タンパク質長	Gly111-Leu228
アプリケーション	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種	Homo sapiens (Human)
性質	Recombinant
エンドトキシンレベル	Please contact with the lab for this information.
純度	>90% as determined by SDS-PAGE.
予測分子量	41.88 kDa
形態	Lyophilized
保存バッファー	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
再構成	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	C33 antigen, CD82, CD82 antigen, IA4, Inducible membrane protein R2, KAI1, Metastasis suppressor Kangai-1, SAR2, ST6, Suppressor of tumorigenicity 6 protein, TSPAN27, Tetraspanin-27, Tspan-27
背景	CD82 antigen is a ~29 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Acts as a attenuator of EGF signaling, facilitating ligand-induced endocytosis of the receptor and its subsequent desensitization. Mechanistically, modulates ligand-induced ubiquitination and trafficking of EGFR via E3 ligase CBL phosphorylation by PKC. Increases cell-matrix adhesion by regulating the membrane organization of integrin alpha4/ITA4. 1. Xu, C. et al. (2009) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23, 3273-88. PMID: 19497983 2. Odintsova, E. et al. (2000) Current biology : CB 10, 1009-12. PMID: 10985391 3. Bu, J. et al. (2022) Acta biochimica et biophysica Sinica 54, 400-408. PMID: 35538033 4. Odintsova, E. et al. (2013) The Journal of biological chemistry 288, 26323-26334. PMID: 23897813 5. Termini, CM. et al. (2014) Molecular biology of the cell 25, 1560-73. PMID: 24623721 6. Mannion, BA. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 2039-47. PMID: 8757325 7. He, B. et al. (2005) The Journal of biological chemistry 280, 3346-54. PMID: 15557282 8. Jee, BK. et al. (2007) Biochemical and biophysical research communications 359, 703-8. PMID: 17560548 9. Bass, R. et al. (2005) The Journal of biological chemistry 280, 14811-8. PMID: 15677461 10. Lee, H. et al. (2023) BMB reports 56, 359-364. PMID: 36945827
注意事項	For research use only