Anti-Human CD82 Recombinant Antibody (SAA1615) (HB018013)

Name: Anti-Human CD82 Recombinant Antibody (SAA1615)
Brand: abinScience
SKU: HB018013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HB018013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1615

Clonality

Monoclonal

Target

IA4, Tspan-27, Metastasis suppressor Kangai-1, Inducible membrane protein R2, Suppressor of tumorigenicity 6 protein, KAI1, TSPAN27, CD82, SAR2, C33 antigen, ST6, Tetraspanin-27, CD82 antigen

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P27701

RRID

Anti-Human CD82 Antibody (SAA1615) (abinScience Cat# HB018013, RRID:AB_3727376)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

CD82 antigen is a ~29 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Acts as a attenuator of EGF signaling, facilitating ligand-induced endocytosis of the receptor and its subsequent desensitization. Mechanistically, modulates ligand-induced ubiquitination and trafficking of EGFR via E3 ligase CBL phosphorylation by PKC. Increases cell-matrix adhesion by regulating the membrane organization of integrin alpha4/ITA4.

1. Xu, C. et al. (2009) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23, 3273-88. PMID: 19497983

2. Odintsova, E. et al. (2000) Current biology : CB 10, 1009-12. PMID: 10985391

3. Bu, J. et al. (2022) Acta biochimica et biophysica Sinica 54, 400-408. PMID: 35538033

4. Odintsova, E. et al. (2013) The Journal of biological chemistry 288, 26323-26334. PMID: 23897813

5. Termini, CM. et al. (2014) Molecular biology of the cell 25, 1560-73. PMID: 24623721

6. Mannion, BA. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 2039-47. PMID: 8757325

7. He, B. et al. (2005) The Journal of biological chemistry 280, 3346-54. PMID: 15557282

8. Jee, BK. et al. (2007) Biochemical and biophysical research communications 359, 703-8. PMID: 17560548

9. Bass, R. et al. (2005) The Journal of biological chemistry 280, 14811-8. PMID: 15677461

10. Lee, H. et al. (2023) BMB reports 56, 359-364. PMID: 36945827

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CD82 Antibody (SAA1615)

References

Datasheet

Anti-Human CD82 Recombinant Antibody (SAA1615).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CD82 Recombinant Antibody (SAA1615) (HB018013)

Overview

Images

References

Datasheet

SDS

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