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Research Grade Vatreptacog alfa (HY060016)

Research Grade Vatreptacog alfa
Research Grade Vatreptacog alfa
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  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
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  • 100mg
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Vista general
Número de catálogoHY060016
Descripción
Vatreptacog alfa (HY060016) is a research-grade recombinant antibody targeting F7. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especiesHuman
AplicacionesELISA, Functional assay, Research in vivo
ClonalidadMonoclonal
IsotipoA recombinant factor VIIa (rFVIIa) analog with three amino acid substitutions (Asp158Val, Val296Glu, and Glu298Met).
Sistema de expresión Mammalian cells
Objetivo F7, Proconvertin, SPCA, Serum prothrombin conversion accelerator, Coagulation factor VII, Eptacog alfa
Nivel de endotoxinas < 10 EU/mg
Pureza >95% as determined by SDS-PAGE.
Purificación Purified by Nickel column.
Número de acceso P08709
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosrFVIIaanalogNN1731, FVIIaDVQ, EptacogAlfa
Fondo

Coagulation factor VII (FVIIa Mutant Version (FVIIaDVQ)) is a ~51 kDa protein. Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium.

1. Osterud, B. et al. (1977) Proceedings of the National Academy of Sciences of the United States of America 74, 5260-4. PMID: 271951
Nota For research use only. Not suitable for clinical or therapeutic use.
Imágenes
  • Research Grade Vatreptacog alfa

    SDS-PAGE

    SDS-PAGE for Research Grade Vatreptacog alfa

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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