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Timely TGFβ signalling inhibition induces notochord

10.1038/s41586-024-08332-w

Affiliations
Tiago Rito, Ashley R G Libby, Madeleine Demuth, Marie-Charlotte Domart, Jake Cornwall-Scoones, James Briscoe

DOI: 10.1038/s41586-024-08332-w

Abstract
The formation of the vertebrate body involves the coordinated production of trunk tissues from progenitors located in the posterior of the embryo. Although in vitro models using pluripotent stem cells replicate aspects of this process

Keywords
TGF-β,notochord

관련 제품

카탈로그 번호 제품명 설명 타겟
HF977096 TGF-β Anti-Human TGFB1/TGF-beta-1 (SRK-181) (HF977096) is a research-grade recombinant antibody targeting Transforming growth factor beta-1 proprotein. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns. Transforming growth factor beta-1 proprotein, LAP, TGF-beta-1, TGFB1, TGFB