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| 카탈로그 번호 | MV819014 | ||||||
|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse NANOG Polyclonal Antibody (MV819014) is a rabbit polyclonal antibody detecting NANOG in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 종 반응성 | Mouse | ||||||
| 응용 분야 | ELISA, IHC, WB | ||||||
| 숙주 종 | Rabbit | ||||||
| 클론성 | Polyclonal | ||||||
| 이소타입 | IgG | ||||||
| 면역원 | E. coli - derived recombinant Mouse NANOG (Thr101-Ile167). | ||||||
| 타겟 | ES cell-associated protein 4, Early embryo specific expression NK-type homeobox protein, Ecat4, Enk, Homeobox protein NANOG, Homeobox transcription factor Nanog, Nanog | ||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||
| 관찰된 분자량 | 37 kDa | ||||||
| 정제 | Purified by antigen affinity column. | ||||||
| 등록번호 | Q80Z64 | ||||||
| 형태 | Liquid | ||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 배경 | Homeobox protein NANOG is a ~34 kDa protein. Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. 1. Hayashi, Y. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 4666-71. PMID: 25825768 | ||||||
| 참고사항 | For research use only. |
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