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Anti-Mouse SREBF1/SREBP1 Polyclonal Antibody (MW748014)

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개요
카탈로그 번호MW748014
설명
Anti-Mouse SREBF1/SREBP1 Polyclonal Antibody (MW748014) is a rabbit polyclonal antibody detecting SREBF1/SREBP1 in ELISA, IHC, WB. Suitable for Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Mouse, Rat
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Mouse SREBF1/SREBP1 (Gly566-Gly1126).
타겟 BHLHD1, Class D basic helix-loop-helix protein 1, Processed sterol regulatory element-binding protein 1, SREBF1, SREBP-1, SREBP1, Sterol regulatory element-binding protein 1, Sterol regulatory element-binding transcription factor 1, Transcription factor SREBF1, bHLHd1
내독소 수준 Please contact with the lab for this information.
정제 Purified by antigen affinity column.
등록번호 Q9WTN3
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
배경

Sterol regulatory element-binding protein 1 (SREBF1/SREBP1) is a ~121 kDa protein. Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 1), which is embedded in the endoplasmic reticulum membrane. Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis and lipid homeostasis.

1. Xu, D. et al. (2020) Nature 580, 530-535. PMID: 32322062
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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