Anti-African clawed frog IRF1 Polyclonal Antibody (ZY164014)

Name: Anti-African clawed frog IRF1 Polyclonal Antibody
Brand: abinScience
SKU: ZY164014
Price: 168 USD
Availability: InStock

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사양:

50ug
100ug

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

ZY164014

설명

Anti-African clawed frog IRF1 Polyclonal Antibody (ZY164014) is a rabbit polyclonal antibody detecting IRF1 in ELISA, IHC, WB. Suitable for Xenopus laevis (African clawed frog).

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Xenopus laevis (African clawed frog)

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant African clawed frog IRF1 (Met1-Arg124).

타겟

IRF-1, IRF1, Interferon regulatory factor 1

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Purified by antigen affinity column.

등록번호

Q6PB00

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Interferon regulatory factor 1 (IRF1) is a ~36 kDa protein. Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target genes and can act as a transcriptional activator and repressor regulating target genes by binding to an interferon-stimulated response element (ISRE) in their promoters. Has an essentail role in IFNG-dependent immunity to mycobacteria. Competes with the transcriptional repressor ZBED2 for binding to a common consensus sequence in gene promoters.

1. Oshima, S. et al. (2004) Molecular and cellular biology 24, 6298-310. PMID: 15226432

2. Dornan, D. et al. (2004) Molecular and cellular biology 24, 10083-98. PMID: 15509808

3. Su, ZZ. et al. (2007) Journal of cellular physiology 213, 502-10. PMID: 17516545

4. Park, J. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 17028-33. PMID: 17942705

5. Bowie, ML. et al. (2008) Advances in experimental medicine and biology 617, 367-74. PMID: 18497060

6. Huang, Y. et al. (2009) PloS one 4, e5397. PMID: 19404407

7. Gao, J. et al. (2010) Cell death and differentiation 17, 699-709. PMID: 19851330

8. Qi, H. et al. (2012) The Journal of biological chemistry 287, 12622-33. PMID: 22367195

9. Somerville, TDD. et al. (2020) Proceedings of the National Academy of Sciences of the United States of America 117, 11471-11482. PMID: 32385160

10. Tanaka, N. et al. (1993) Molecular and cellular biology 13, 4531-8. PMID: 7687740

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-African clawed frog IRF1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-African clawed frog IRF1 Polyclonal Antibody (ZY164014)

개요

이미지

참고 문헌

데이터시트

SDS