Anti-Mouse MPEG1 Polyclonal Antibody (MS702014)

Name: Anti-Mouse MPEG1 Polyclonal Antibody
Brand: abinScience
SKU: MS702014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

MS702014

설명

Anti-Mouse MPEG1 Polyclonal Antibody (MS702014) is a rabbit polyclonal antibody detecting MPEG1 in ELISA, IHC, WB. Suitable for Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse MPEG1 (Gly379-Lys576).

타겟

MPEG1, Macrophage gene 1 protein, Macrophage-expressed gene 1 protein, Macrophage-expressed gene 1 protein, processed form, Mpg-1, P-2, Perforin-2

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

A1L314

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Macrophage-expressed gene 1 protein (MPEG1) is a ~78 kDa protein. Pore-forming protein involved in both innate and adaptive immunity. Plays a central role in antigen cross-presentation in dendritic cells by forming a pore in antigen-containing compartments, thereby promoting delivery of antigens for cross-presentation. Also involved in innate immune response following bacterial infection; shows antibacterial activity against a wide spectrum of Gram-positive, Gram-negative and acid-fast bacteria. Reduces the viability of the intracytosolic pathogen L.monocytogenes by inhibiting acidification of the phagocytic vacuole of host cells which restricts bacterial translocation from the vacuole to the cytosol. Required for the antibacterial activity of reactive oxygen species and nitric oxide.

1. Fields, KA. et al. (2013) Infection and immunity 81, 3045-54. PMID: 23753625

2. McCormack, RM. et al. (2015) eLife 4. PMID: 26402460

3. McCormack, RM. et al. (2017) JCI insight 2. PMID: 28422754

4. Strbo, N. et al. (2019) Experimental dermatology 28, 225-232. PMID: 30609079

5. Pang, SS. et al. (2019) Nature communications 10, 4288. PMID: 31537793

6. Merselis, LC. et al. (2020) Frontiers in immunology 11, 601584. PMID: 33224153

참고사항

For research use only

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참고 문헌

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Anti-Mouse MPEG1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse MPEG1 Polyclonal Antibody (MS702014)

개요

이미지

참고 문헌

데이터시트

SDS

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