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| 카탈로그 번호 | MY500014 | ||||||
|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse COX4/COX4I1 Polyclonal Antibody (MY500014) is a rabbit polyclonal antibody detecting COX4/COX4I1 in ELISA, IHC, WB. Suitable for Mouse, Rat.
Highlights
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| 종 반응성 | Mouse, Rat | ||||||
| 응용 분야 | ELISA, IHC, WB | ||||||
| 숙주 종 | Rabbit | ||||||
| 클론성 | Polyclonal | ||||||
| 이소타입 | IgG | ||||||
| 면역원 | E. coli - derived recombinant Mouse COX4/COX4I1 (Met1-Glu99). | ||||||
| 타겟 | COX IV-1, Cox4, Cox4a, Cox4i1, Coxiv, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase subunit IV isoform 1 | ||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||
| 관찰된 분자량 | ~17 kDa | ||||||
| 정제 | Purified by antigen affinity column. | ||||||
| 등록번호 | P19783 | ||||||
| 형태 | Liquid | ||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 배경 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4/COX4I1) is a ~19 kDa protein. Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix. | ||||||
| 참고사항 | For research use only. |
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