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Research Grade Efaxaglutide Alfa (HW328076)

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사양:
  • 100ug
  • 1mg
수량:
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  • 개요

  • 이미지

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  • 데이터시트

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개요
카탈로그 번호HW328076
설명
Research Grade Efaxaglutide Alfa (HW328076) is a monoclonal antibody detecting GLP-1R.
종 반응성Human
응용 분야ELISA, FCM, Functional assay
클론성Monoclonal
이소타입GLP1-exendin 4-Fc
발현 시스템 Mammalian cells
성질 Recombinant
타겟 GCG, GLP-1, GLP-1(7-36), GLP-1(7-37), GLP-2, GRPP, Glicentin, Glicentin-related polypeptide, Glucagon, Glucagon-like peptide 1, Glucagon-like peptide 1(7-36), Glucagon-like peptide 1(7-37), Glucagon-like peptide 2, Incretin hormone, OXM, OXY, Oxyntomodulin, Pro-glucagon, Exenatide, Exendin-4
내독소 수준 < 10 EU/mg as determined by LAL method.
순도 >95% as determined by SDS-PAGE.
정제 Protein A/G purified from cell culture supernatant.
등록번호 P01275 & P26349
형태 Liquid
저장 완충액 0.01M PBS pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt..
대체 이름CAS: 3069923-11-8
배경

Glucagon-like peptide 1 receptor (GLP1R) is a ~53 kDa protein. G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1.

1. Underwood, CR. et al. (2010) The Journal of biological chemistry 285, 723-30. PMID: 19861722
2. Lau, J. et al. (2015) Journal of medicinal chemistry 58, 7370-80. PMID: 26308095
3. Hennen, S. et al. (2016) Scientific reports 6, 26236. PMID: 27196125
4. Song, G. et al. (2017) Nature 546, 312-315. PMID: 28514449
5. van Eyll, B. et al. (1994) FEBS letters 348, 7-13. PMID: 7517895
6. Graziano, MP. et al. (1993) Biochemical and biophysical research communications 196, 141-6. PMID: 8216285
7. Thorens, B. et al. (1993) Diabetes 42, 1678-82. PMID: 8405712
참고사항 For research use only. Not suitable for clinical or therapeutic use.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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