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| 카탈로그 번호 | HV181013 |
|---|---|
| 설명 |
Anti-TSG101 Recombinant Antibody (SRR1036) (HV181013) is a rabbit monoclonal antibody detecting TSG101 in WB, IHC, IF, IP, FCM. Suitable for Human, Mouse, Rat.
Highlights
|
| 종 반응성 | Human, Mouse, Rat |
| 응용 분야 | WB, IHC, IF, IP, FCM |
| 숙주 종 | Rabbit |
| 클론성 | Monoclonal |
| 이소타입 | IgG |
| 클론 ID | SRR1036 |
| 테스트된 응용 분야 | WB, IHC, IF, IP, FCM |
| 타겟 | ESCRT-I complex subunit TSG101, TSG101, Tumor susceptibility gene 101 protein |
| 내독소 수준 | < 10 EU/mg as determined by LAL method. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | Q99816, Q61187, Q6IRE4 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4, 50% glycerol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Tumor susceptibility gene 101 protein (TSG101) is a ~43 kDa protein. Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. 1. Baietti, MF. et al. (2012) Nature cell biology 14, 677-85. PMID: 22660413 2. Nabhan, JF. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 4146-51. PMID: 22315426 |
| 참고사항 | For research use only. |
| Isotype Control | TF690107 |
Western blot analysis was performed using anti-TSG101 antibody at 1:1000 on various samples.
Lane 1: Hela cell lysate
Lane 2: HepG2 cell lysate
Lane 3: Jurkat cell lysate
Lane 4: K562 cell lysate
Lane 5: NIH3T3 cell lysate
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