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| 카탈로그 번호 | MT209012 |
|---|---|
| 설명 |
Recombinant Mouse BCAT2 Protein, N-His (MT209012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | O35855 |
| 단백질 길이 | Asp36-Val393 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Mus musculus (Mouse) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | BCAT(m), Bcat2, Bcatm, Branched-chain-amino-acid aminotransferase, mitochondrial, EC:2.6.1.42, Eca40 |
| 배경 | Branched-chain-amino-acid aminotransferase, mitochondrial is a ~44 kDa protein. Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. Branched chain amino acid catabolism plays a role in adipocyte differentiation by providing lipogenic acetyl-CoA pools in differentiated adipocytes. Mechanistically, acetyl-CoA derived from branched chain amino acid catabolism is used by EP300/p300 to acetylate and inhibit PRDM16, thereby preventing adipose tissue browning. May also function as a transporter of branched chain alpha-keto acids. 1. Wu, JY. et al. (2004) The Journal of clinical investigation 113, 434-40. PMID: 14755340 2. She, P. et al. (2007) Cell metabolism 6, 181-94. PMID: 17767905 3. Ma, QX. et al. (2022) Nature metabolism 4, 106-122. PMID: 35075301 |
| 참고사항 | For research use only |
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