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| 카탈로그 번호 | MW497012 |
|---|---|
| 설명 |
Recombinant Mouse FASLG Protein, N-His (MW497012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | P41047 |
| 단백질 길이 | Arg142-Leu279 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Mus musculus (Mouse) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 18.12 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | ADAM10-processed FasL form, APL, Apt1lg1, CD178, CD95 ligand, CD95-L, Cd95l, Fas antigen ligand, Fas ligand, FasL, FasL ICD, FasL intracellular domain, Fasl, Faslg, Receptor-binding FasL ectodomain, SPA, SPPL2A-processed FasL form, Soluble Fas ligand, Tnfsf6, Tumor necrosis factor ligand superfamily member 6, Tumor necrosis factor ligand superfamily member 6, membrane form, Tumor necrosis factor ligand superfamily member 6, soluble form, gld, sFasL |
| 배경 | Tumor necrosis factor ligand superfamily member 6 is a ~31 kDa protein. Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis also has a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. 1. Takahashi, T. et al. (1994) Cell 76, 969-76. PMID: 7511063 2. O' Reilly, LA. et al. (2009) Nature 461, 659-63. PMID: 19794494 3. Arase, H. et al. (1995) The Journal of experimental medicine 181, 1235-8. PMID: 7532682 4. Georgantas, RW. et al. (2000) Human gene therapy 11, 851-8. PMID: 10779162 |
| 참고사항 | For research use only |
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