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Mouse MMP-14/MT1-MMP Recombinant Protein (N-His) (MW299012)

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사양:
  • 50ug
  • 100ug
  • 1mg
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개요
카탈로그 번호MW299012
설명
Mouse MMP-14/MT1-MMP Recombinant Protein (N-His) (MW299012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE. by SDS-PAGE.
Highlights
  • ●Recombinant — Consistent lot-to-lot performance.
  • ●High Purity — >90% as determined by SDS-PAGE. by SDS-PAGE for demanding downstream applications.
발현 시스템E. coli
등록번호P53690
단백질 길이Pro35-Tyr283
응용 분야ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종Mus musculus (Mouse)
성질 Recombinant
내독소 수준 Please contact with the lab for this information.
순도 >90% as determined by SDS-PAGE.
예측 분자량 30.57 kDa
형태 Lyophilized
저장 완충액 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

재구성 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름EC:3.4.24.80, MMP-14, MMP-X1, MMP14, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1, Matrix metalloproteinase-14, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase
배경

Matrix metalloproteinase-14 (MMP14) is a ~65 kDa protein. Endopeptidase that degrades various components of the extracellular matrix such as collagen. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. Activates progelatinase A/MMP2, thereby acting as a positive regulator of cell growth and migration. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. May be involved in actin cytoskeleton reorganization by cleaving PTK7.

1. Sato, H. et al. (1994) Nature 370, 61-5. PMID: 8015608
2. Gu, G. et al. (2012) Journal of cellular biochemistry 113, 1013-21. PMID: 22065321
3. Noda, K. et al. (2003) Investigative ophthalmology & visual science 44, 2163-70. PMID: 12714657
4. Golubkov, VS. et al. (2010) The Journal of biological chemistry 285, 35740-9. PMID: 20837484
5. Jin, G. et al. (2011) The EMBO journal 30, 2281-93. PMID: 21572390
6. Cork, SM. et al. (2012) Oncogene 31, 5144-52. PMID: 22330140
7. Chow, CFW. et al. (2022) Nature metabolism 4, 203-212. PMID: 35177851
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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