Anti-ABCB7 Polyclonal Antibody (HF952014)

Name: Anti-ABCB7 Polyclonal Antibody
Brand: abinScience
SKU: HF952014
Price: 168 USD
Availability: InStock

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개요
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SDS

개요

카탈로그 번호

HF952014

설명

Anti-ABCB7 Polyclonal Antibody (HF952014) is a rabbit polyclonal antibody detecting ABCB7 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ABCB7 (Val472-Cys752).

타겟

ABC transporter 7 protein, ABC7, ATP-binding cassette sub-family B member 7, mitochondrial, ATP-binding cassette transporter 7, ABCB7

정제

Purified by antigen affinity column.

등록번호

O75027

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Iron-sulfur clusters transporter ABCB7, mitochondrial is a ~82 kDa protein. Exports glutathione-coordinated iron-sulfur clusters such as [2Fe-2S]-(GS)4 cluster from the mitochondria to the cytosol in an ATP-dependent manner allowing the assembly of the cytosolic iron-sulfur (Fe/S) cluster-containing proteins and participates in iron homeostasis. Moreover, through a functional complex formed of ABCB7, FECH and ABCB10, also plays a role in the cellular iron homeostasis, mitochondrial function and heme biosynthesis. In cardiomyocytes, regulates cellular iron homeostasis and cellular reactive oxygen species (ROS) levels through its interaction with COX4I1. May also play a role in hematopoiesis.

1. Allikmets, R. et al. (1999) Human molecular genetics 8, 743-9. PMID: 10196363

2. Cavadini, P. et al. (2007) Blood 109, 3552-9. PMID: 17192393

3. Pearson, SA. et al. (2021) Archives of biochemistry and biophysics 697, 108661. PMID: 33157103

4. Maio, N. et al. (2019) Haematologica 104, 1756-1767. PMID: 30765471

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-ABCB7 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-ABCB7 Polyclonal Antibody (HF952014)

개요

이미지

참고 문헌

데이터시트

SDS