Anti-ABCE1 Polyclonal Antibody (HX969014)

Name: Anti-ABCE1 Polyclonal Antibody
Brand: abinScience
SKU: HX969014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HX969014

설명

Anti-ABCE1 Polyclonal Antibody (HX969014) is a rabbit polyclonal antibody detecting ABCE1 in ELISA, IHC, WB. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ABCE1 (Ile389-Asn556).

타겟

HuHP68, RNS4I, RNASEL1, RNase L inhibitor, 2'-5'-oligoadenylate-binding protein, RLI, ABCE1, ATP-binding cassette sub-family E member 1, RNASELI, Ribonuclease 4 inhibitor

정제

Purified by antigen affinity column.

등록번호

P61221

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

ATP-binding cassette sub-family E member 1 (ABCE1) is a ~67 kDa protein. Nucleoside-triphosphatase (NTPase) involved in ribosome recycling by mediating ribosome disassembly. Able to hydrolyze ATP, GTP, UTP and CTP. Splits ribosomes into free 60S subunits and tRNA- and mRNA-bound 40S subunits. Acts either after canonical termination facilitated by release factors (ETF1/eRF1) or after recognition of stalled and vacant ribosomes by mRNA surveillance factors (PELO/Pelota). Involved in the No-Go Decay (NGD) pathway: recruited to stalled ribosomes by the Pelota-HBS1L complex, and drives the disassembly of stalled ribosomes, followed by degradation of damaged mRNAs as part of the NGD pathway.

1. Pisarev, AV. et al. (2010) Molecular cell 37, 196-210. PMID: 20122402

2. Pisareva, VP. et al. (2011) The EMBO journal 30, 1804-17. PMID: 21448132

3. Wu, Z. et al. (2018) Cell metabolism 28, 130-144.e7. PMID: 29861391

5. Le Roy, F. et al. (2001) The Journal of biological chemistry 276, 48473-82. PMID: 11585831

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-ABCE1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-ABCE1 Polyclonal Antibody (HX969014)

개요

이미지

참고 문헌

데이터시트

SDS