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| 카탈로그 번호 | HW364014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-ABCG1 Polyclonal Antibody (HW364014) is a rabbit polyclonal antibody detecting ABCG1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human ABCG1 (Met1-His353). | ||||||||
| 타겟 | ATP-binding cassette transporter 8, ABC8, ATP-binding cassette sub-family G member 1, ABCG1, WHT1, White protein homolog | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P45844 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | ATP-binding cassette sub-family G member 1 (ABCG1) is a ~75 kDa protein. Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP. The lipid efflux is ALB-dependent. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. 1. Engel, T. et al. (2007) FEBS letters 581, 1673-80. PMID: 17408620 2. Gu, HM. et al. (2014) Biochimica et biophysica acta 1841, 847-58. PMID: 24576892 3. Kobayashi, A. et al. (2006) Journal of lipid research 47, 1791-802. PMID: 16702602 | ||||||||
| 참고사항 | For research use only. |
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