

| 카탈로그 번호 | HS771014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-ACOX1 Polyclonal Antibody (HS771014) is a rabbit polyclonal antibody detecting ACOX1 in ELISA, IHC, WB. Suitable for Bovine, Cavia porcellus, Human, Pongo abelii, and Rat.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human ACOX1 (Tyr275-Leu660). | ||||||||
| 타겟 | ACOX1, Palmitoyl-CoA oxidase, SCOX, AOX, ACOX, Peroxisomal acyl-coenzyme A oxidase 1, Straight-chain acyl-CoA oxidase | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q15067 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) is a ~74 kDa protein. Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs that have a saturated bond between C2 and C3 (2,3-saturated acyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs), and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2)). 1. Ferdinandusse, S. et al. (2004) Journal of lipid research 45, 1104-11. PMID: 15060085 2. Ferdinandusse, S. et al. (2007) Human mutation 28, 904-12. PMID: 17458872 3. Oaxaca-Castillo, D. et al. (2007) Biochemical and biophysical research communications 360, 314-9. PMID: 17603022 4. Chung, HL. et al. (2020) Neuron 106, 589-606.e6. PMID: 32169171 5. Morita, A. et al. (2021) Brain & development 43, 475-481. PMID: 33234382 6. Chu, R. et al. (1995) The Journal of biological chemistry 270, 4908-15. PMID: 7876265 | ||||||||
| 참고사항 | For research use only. |
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