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| 카탈로그 번호 | HS862014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Adiponectin/ACRP30/ADIPOQ Polyclonal Antibody (HS862014) is a rabbit polyclonal antibody detecting Adiponectin in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human Adiponectin/ACRP30/ADIPOQ (Glu19-Asn244). | ||||||||
| 타겟 | Adiponectin, ACRP30, GBP28, Adipose most abundant gene transcript 1 protein, ACDC, APM1, ADIPOQ, apM-1, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, Adipocyte, C1q and collagen domain-containing protein, Gelatin-binding protein | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q15848 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Adiponectin (ADPN) is a ~26 kDa protein. Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. | ||||||||
| 참고사항 | For research use only. |
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