

| 카탈로그 번호 | HT001014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-AKR1B10 Polyclonal Antibody (HT001014) is a rabbit polyclonal antibody detecting AKR1B10 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human AKR1B10 (Met1-Tyr316). | ||||||||
| 타겟 | SI reductase, ARP, Small intestine reductase, ARL-1, Aldose reductase-related protein, Aldose reductase-like, AKR1B11, Aldo-keto reductase family 1 member B10, hARP, AKR1B10 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O60218 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Aldo-keto reductase family 1 member B10 (AKR1B10) is a ~36 kDa protein. Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays strong enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal. Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls). Displays no reductase activity towards glucose. 1. Crosas, B. et al. (2003) The Biochemical journal 373, 973-9. PMID: 12732097 2. Gallego, O. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 20764-9. PMID: 18087047 3. Martin, HJ. et al. (2009) Chemico-biological interactions 178, 145-50. PMID: 19013440 4. Zhong, L. et al. (2009) Biochemical and biophysical research communications 387, 245-50. PMID: 19563777 5. Cao, D. et al. (1998) The Journal of biological chemistry 273, 11429-35. PMID: 9565553 | ||||||||
| 참고사항 | For research use only. |
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