Anti-ALDH1A2 Polyclonal Antibody (HF656014)

Name: Anti-ALDH1A2 Polyclonal Antibody
Brand: abinScience
SKU: HF656014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HF656014

설명

Anti-ALDH1A2 Polyclonal Antibody (HF656014) is a rabbit polyclonal antibody detecting ALDH1A2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ALDH1A2 (Met1-Val422).

타겟

Retinaldehyde-specific dehydrogenase type 2, ALDH1A2, Retinal dehydrogenase 2, RALDH2, RALDH(II), Aldehyde dehydrogenase family 1 member A2, RALDH 2, RalDH2

정제

Purified by antigen affinity column.

등록번호

O94788

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Retinal dehydrogenase 2 (ALDH1A2) is a ~56 kDa protein. Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively. Retinoate signaling is critical for the transcriptional control of many genes, for instance it is crucial for initiation of meiosis in both male and female (Probable). Recognizes retinal as substrate, both in its free form and when bound to cellular retinol-binding protein. Can metabolize octanal and decanal, but has only very low activity with benzaldehyde, acetaldehyde and propanal. Displays complete lack of activity with citral.

1. Chen, Y. et al. (2018) ACS chemical biology 13, 582-590. PMID: 29240402

2. Beecroft, SJ. et al. (2021) Human mutation 42, 506-519. PMID: 33565183

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-ALDH1A2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-ALDH1A2 Polyclonal Antibody (HF656014)

개요

이미지

참고 문헌

데이터시트

SDS

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