Anti-ALDH7A1 Polyclonal Antibody (HW546014)

Name: Anti-ALDH7A1 Polyclonal Antibody
Brand: abinScience
SKU: HW546014
Price: 96 USD
Availability: InStock

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HW546014

설명

Anti-ALDH7A1 Polyclonal Antibody (HW546014) is a rabbit polyclonal antibody detecting ALDH7A1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ALDH7A1 (Met1-Gln539).

타겟

ALDH7A1, Delta1-piperideine-6-carboxylate dehydrogenase, Antiquitin-1, P6c dehydrogenase, Alpha-AASA dehydrogenase, Alpha-aminoadipic semialdehyde dehydrogenase, Aldehyde dehydrogenase family 7 member A1, Betaine aldehyde dehydrogenase, ATQ1

정제

Purified by antigen affinity column.

등록번호

P49419

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) is a ~58 kDa protein. Aldehyde dehydrogenase enzyme that mediates important protective effects. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in cellular defense against hyperosmotic stress by metabolizing betaine aldehyde to betaine, an important cellular osmolyte and methyl donor.

1. Mills, PB. et al. (2006) Nature medicine 12, 307-9. PMID: 16491085

2. Brocker, C. et al. (2010) The Journal of biological chemistry 285, 18452-63. PMID: 20207735

3. Mills, PB. et al. (2010) Brain : a journal of neurology 133, 2148-59. PMID: 20554659

4. Brocker, C. et al. (2011) Chemico-biological interactions 191, 269-77. PMID: 21338592

5. Luo, M. et al. (2015) ACS chemical biology 10, 693-7. PMID: 25554827

6. Laciak, AR. et al. (2020) The FEBS journal 287, 173-189. PMID: 31302938

7. Laciak, AR. et al. (2020) Journal of inherited metabolic disease 43, 635-644. PMID: 31652343

8. Korasick, DA. et al. (2024) Chemico-biological interactions 394, 110993. PMID: 38604394

9. Yang, JS. et al. (2025) Cell 188, 2569-2585.e20. PMID: 40233740

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-ALDH7A1 polyclonal antibody at 1µg/ml on various samples.
Lane 1: 293T cell lysate
Lane 2: Mouse liver lysate
Lane 3: Rat liver lysate
Lane 4: Rat kidney lysate

참고 문헌

데이터시트

Anti-ALDH7A1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-ALDH7A1 Polyclonal Antibody (HW546014)

개요

이미지

참고 문헌

데이터시트

SDS