

| 카탈로그 번호 | HB957014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-AOAH Polyclonal Antibody (HB957014) is a rabbit polyclonal antibody detecting AOAH in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human AOAH (Ser24-Gln300). | ||||||||
| 타겟 | AOAH, Acyloxyacyl hydrolase | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P28039 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Acyloxyacyl hydrolase (AOAH) is a ~65 kDa protein. Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides. By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses. In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria. 1. Hagen, FS. et al. (1991) Biochemistry 30, 8415-23. PMID: 1883828 2. Gorelik, A. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E896-E905. PMID: 29343645 3. Staab, JF. et al. (1994) The Journal of biological chemistry 269, 23736-42. PMID: 8089145 | ||||||||
| 참고사항 | For research use only. |

Western blot analysis was performed using anti-AOAH polyclonal antibody at 1ug/mL on various samples.
Lane 1: HL-60 cell lysate
Lane 2: THP-1 cell lysate
Lane 3: A549 cell lysate
Lane 4: HUVEC cell lysate
Lane 5: BxPC-3 cell lysate


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