

| 카탈로그 번호 | HB958014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-AOC1/DAO Polyclonal Antibody (HB958014) is a rabbit polyclonal antibody detecting AOC1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human AOC1/DAO (Glu20-Trp322). | ||||||||
| 타겟 | AOC1, ABP1, DAO, Kidney amine oxidase, Histaminase, Amiloride-sensitive amine oxidase [copper-containing], Amiloride-binding protein 1, Diamine oxidase, KAO, DAO1, Amine oxidase copper domain-containing protein 1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P19801 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Diamine oxidase [copper-containing] (AOC1/DAO) is a ~85 kDa protein. Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Its preferred substrates are the diamines histamine and 1-methylhistamine and it could therefore play a role in allergic and immune responses. Has a broad specificity for diamines and can also act on cadaverine and putrescine, two products of amino acid catabolism. It could also act on polyamines, like spermidine and spermine though less efficiently, and regulate various biological processes. 1. Elmore, BO. et al. (2002) Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 7, 565-79. PMID: 12072962 2. McGrath, AP. et al. (2009) Biochemistry 48, 9810-22. PMID: 19764817 3. Hölttä, E. et al. (1975) The Biochemical journal 145, 373-8. PMID: 239684 4. Novotny, WF. et al. (1994) The Journal of biological chemistry 269, 9921-5. PMID: 8144586 | ||||||||
| 참고사항 | For research use only. |
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