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| 카탈로그 번호 | HW605014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human AP2S1 (Met1-Glu142). | ||||||||
| 타겟 | Adaptor-related protein complex 2 subunit sigma, Clathrin assembly protein 2 sigma small chain, HA2 17 kDa subunit, AP2S1, Clathrin coat-associated protein AP17, Clathrin coat assembly protein AP17, AP-2 complex subunit sigma, Adaptor protein complex AP-2 subunit sigma, CLAPS2, AP17, Sigma2-adaptin, Plasma membrane adaptor AP-2 17 kDa protein | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P53680 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | AP-2 complex subunit sigma (AP2S1) is a ~17 kDa protein. Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. | ||||||||
| 참고사항 | For research use only. |
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