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Anti-AP4M1 Polyclonal Antibody (HC009014)

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개요
카탈로그 번호HC009014
설명
Anti-AP4M1 Polyclonal Antibody (HC009014) is a rabbit polyclonal antibody detecting AP-4 complex subunit mu-1; AP-4 adaptor complex mu subunit; Adaptor-related protein complex 4 subunit mu-1; Mu subunit of AP-4; Mu-adaptin-related protein 2; mu-ARP2; Mu4-adaptin; mu4; AP4M1; MUARP2 in ELISA, IHC, WB. Suitable for Human, Bovine, Dog, Rat, and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Human, Mouse, Rat
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant human AP4M1 (Lys184-Ile453).
타겟 AP-4 complex subunit mu-1; AP-4 adaptor complex mu subunit; Adaptor-related protein complex 4 subunit mu-1; Mu subunit of AP-4; Mu-adaptin-related protein 2; mu-ARP2; Mu4-adaptin; mu4; AP4M1; MUARP2
내독소 수준 Please contact with the lab for this information.
정제 Purified by antigen affinity column.
등록번호 O00189, Q29RY8, E2RED8, Q2PWT8, Q9JKC7
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

AP-4 complex subunit mu-1 (AP4M1) is a ~49 kDa protein. Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons.

1. Dell'Angelica, EC. et al. (1999) The Journal of biological chemistry 274, 7278-85. PMID: 10066790
2. Hirst, J. et al. (1999) Molecular biology of the cell 10, 2787-802. PMID: 10436028
3. Aguilar, RC. et al. (2001) The Journal of biological chemistry 276, 13145-52. PMID: 11139587
4. Simmen, T. et al. (2002) Nature cell biology 4, 154-9. PMID: 11802162
5. Burgos, PV. et al. (2010) Developmental cell 18, 425-36. PMID: 20230749
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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