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| 카탈로그 번호 | HT226014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-AQP9 Polyclonal Antibody (HT226014) is a rabbit polyclonal antibody detecting AQP9 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human AQP9 (Tyr125-Leu158). | ||||||||
| 타겟 | AQP-9, SSC1, Small solute channel 1, Aquaporin-9, AQP9, Aquaglyceroporin-9 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O43315 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Aquaporin-9 (AQP9) is a ~31 kDa protein. Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. AQP9 is the primary route for glycerol uptake in hepatocytes, supporting hepatic gluconeogenesis. It exhibits broad specificity and may transport various small, non-charged solutes, including carbamides, polyols, purines, and pyrimidines. AQP9 may also facilitate hepatic urea extrusion. Due to its permeability to lactate, AQP9 might participate in the astrocyte-to-neuron lactate shuttle, supplying neurons with energy. 1. Tsukaguchi, H. et al. (1999) The American journal of physiology 277, F685-96. PMID: 10564231 2. Gotfryd, K. et al. (2018) Nature communications 9, 4749. PMID: 30420639 3. Geistlinger, K. et al. (2022) Life (Basel, Switzerland) 12. PMID: 35054513 4. Ishibashi, K. et al. (1998) Biochemical and biophysical research communications 244, 268-74. PMID: 9514918 | ||||||||
| 참고사항 | For research use only. |
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